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map3® Chips Allograft

Map3® cellular allogeneic bone graft is a natural and safe alternative to autograft that supports the body’s innate healing mechanisms and provides the scaffold and signals to facilitate bone growth. The implant contains the three essential elements needed to generate and maintain new bone.

  • Cortical cancellous bone chips supply a three dimensional osteoconductive scaffold
  • Demineralized bone matrix demonstrates verified osteoinductive potential*
  • Cryogenically preserved, viable multipotent adult progenitor (MAPC®)-class cells provide osteogenic and angiogenic signals to support the bone healing process.

*DBM or representative finished implant is either assayed in vivo in the modified athymic nude rat for bone formation or in vitro for endogenous BMP-2 as a surrogate test marker for osteoinductive potential. Because the combination of various proteins is responsible for osteoinductive potential, DBM when assayed in vitro, is also screened for the presence of BMP-7. Findings from an in vitro assay or animal model are not necessarily predictive of human clinical results.


Specifications Preservation
2cc Frozen
5cc Frozen
10cc Frozen

The scaffold is sterilized through the Cancelle® SP DBM Sterilization Process.

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Implant Definitions

Allograft
Tissue (e.g., bone, tendons, ligaments, skin, heart valves) taken from one person for transplantation into another.
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Autograft
Tissue surgically removed from one area of a person’s body and transplanted in another site on the same person.
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Xenograft
Animal-derived tissue (e.g., bovine or porcine) that is transplanted to a human recipient.
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