TETRAfuse® 3D Technology is designed to
participate in fusion1,2,†
Studies have shown nano-roughened surfaces enhance
protein absorption and bioactivity, improving osteoblast
adhesion and tissue growth.
3-6 Additionally, an average pore size greater than 300μm is recommended to
enhance new bone formation.
- 3D printed nano-rough surface
- 530μm average pore diameter
- Macro/Micro structures designed to allow more cells to attach to more of the implant
In an ovine model, histological review of TETRAfuse 3D Technology samples showed deeper implant osseointegration and
more notable trabecular bone ingrowth (Table 1) compared to PEEK and titanium (Ti) coated PEEK.
TABLE 1: Results from TETRAfuse Ovine Study
† Performance data from animal studies may not be representative of performance in humans.
1. Data on file at RTI Surgical, Inc. Animal and in vitro data may not be representative of clinical experience.
2. Data on file at RTI Surgical, Inc.
3. Webster TJ, Ejiofor JU. Increased osteoblast adhesion on nanophase metals: Ti, Ti6Al4V, and CoCrMo, Biomaterials. 2004, 25: 4731e4739.
4. Bagherifard S, Webster TJ, et. al. The influence of nanostructured features on bacterial adhesion and bone cell functions on severely shot peened 316L stainless steel. Biomaterials. 2015, 73: 185e197.
5. Izquierdo-Barba I, Vallet-Regí M, et. al. Nanocolumnar coatings with selective behavior towards osteoblast and Staphylococcus aureus proliferation. Acta Biomater. 2015, 15: 20-8.
6. Colon G, Ward BC, Webster TJ. Increased osteoblast and decreased Staphylococcus epidermidis functions on nanophase ZnO and TiO2. J Biomed Mater Res A. 2006, 1;78(3):595-604
7. Karageorgiou V, Kaplan D. Porosity of 3D biomaterial scaffolds and osteogenesis. Biomaterials. 2005 Sep;26(27):5474-91